PubMed COVID-19 Clinical Care
821 - 830 of 3588 results found
Immunocompetent Mice As a Model for Preclinical Studies of mRNA Vaccine Immunogenicity
Description
Conducting preclinical studies of mRNA vaccines is complicated by the lack of relevant animal models of the human immune system. Immunocompetent mice are widely used in biomedical research. However, critical differences in the genetics and immune
Invasive Pneumococcal Disease After 2 Decades of Pneumococcal Conjugate Vaccine Use
Description
CONCLUSIONS: Robust ongoing surveillance networks are critical for identifying emerging serotypes and development of next-generation vaccine formulations.
Impact of the COVID-19 Pandemic on Health Care Utilization in the Vaccine Safety Datalink: Retrospective Cohort Study
Description
CONCLUSIONS: Telehealth services became a mainstay of the health care system during the late COVID-19 pandemic period. Inpatient and ED visits returned to pre-pandemic levels, although they remained low among members without evidence of COVID-19. Our
Inhibition of the KCa2 potassium channel in atrial fibrillation: a randomized phase 2 trial
Description
Existing antiarrhythmic drugs to treat atrial fibrillation (AF) have incomplete efficacy, contraindications and adverse effects, including proarrhythmia. AP30663, an inhibitor of the K(Ca)2 channel, has demonstrated AF efficacy in animals; however
Inactivated whole virion vaccine protects K18-hACE2 Tg mice against Omicron SARS-CoV-2 variant via cross-reactive T cells and non-neutralizing antibody responses
Description
COVID-19 is a systemic inflammatory disease initiated by SARS-CoV-2 virus infection. Multiple vaccines against Wuhan variant of SARS-CoV-2 have been developed including a whole virion beta-propiolactone-inactivated vaccine based on B.1.1 strain
Impact of COVID-19 on American Family Physicians' Intent to Retreat from Clinical Care
Description
CONCLUSION: The COVID-19 pandemic impacted family physician's career plans. Remedying burnout is a high-yield opportunity for retaining clinically active family physicians. Physicians retreating from clinical medicine related to changing life's
Issues in Ethics in Orthopaedic Surgery Following the COVID-19 Pandemic
Description
The COVID-19 pandemic has caused changes in health care as well as human suffering, and consideration of the principles of ethics can build a foundation to consider dilemmas that have arisen. Diversity, equity, and inclusion have become key issues
Identifying modifiable factors associated with COVID-19 vaccine hesitancy and acceptance among cancer patients in Jordan
Description
CONCLUSION: Peer encouragement, awareness, and fear emerged as the primary modifiable factors associated with greater vaccine acceptance by patients with active malignancies. Study results suggest that providing personalized and tailored information
